Generic Valcyte (Valgan Tablets) - Product Information
Generic Valcyte (Valgan Tablets) is used for the treatment of CMV (cytomegalovirus) retinitis in patients with acquired immunodeficiency syndrome (AIDS). It is also used for prevention of CMV disease in kidney, heart, or kidney-pancreas transplant patients at high risk.
Valgan tablets are manufactured by Cipla Ltd. in the strengths of 450 mg.
Name of the Drug
We supply original Valgan tablets manufactured by Cipla Ltd..
Manufacturer of Valgan Tablets
Cipla Ltd.
Website: cipla.com
Active Ingredient present in Valgan Tablets
The active ingredient present in Valgan tablets is Valganciclovir Hydrochloride. Each tablet contains Valganciclovir Hydrochloride equivalent to 450 mg of Valganciclovir.
Uses of Generic Valcyte (Valgan by Cipla)
Valgan (Valganciclovir 450 mg) is used in adults to treat cytomegalovirus (CMV) retinitis in people who have acquired immunodeficiency syndrome (AIDS) and to prevent cytomegalovirus (CMV) disease in people who have received a heart, kidney, or kidney-pancreas transplant and who have a high risk for getting CMV disease.
When CMV virus infects the eyes, it is called CMV retinitis. If CMV retinitis is left untreated, it can cause blindness.
Clear Sky Online Pharmacy dispense the following medicine:
Global reference brand name : Generic Valcyte by Roche
Brand name dispensed by Clearskypharmacy : Valgan
Manufacturer : Cipla
Active ingredient and strength(s) : Valganciclovir 450 mg
Note: We also offer the original Valcyte manufactured by Roche. Kindly email us for special offer.
Valganciclovir Dose
Valgan tablets should be taken with food. The recommended Valganciclovir dose in adult Patients with normal renal function is given below:
Treatment of CMV Retinitis:
Starting : The recommended starting dose is 900 mg (two 450 mg tablets) twice a day for 21 days. Maintenance: Following initial treatment, or in adult patients with inactive CMV retinitis, the recommended dose is 900 mg (two 450 mg tablets) once a day.
Prevention of CMV Disease:
For adult patients who have received a heart or kidney-pancreas transplant, the recommended Valgan dose is 900 mg (two 450 mg tablets) once a day, starting within 10 days of transplantation until 100 days post-transplantation.
For adult patients who have received a kidney transplant, the recommended Valganciclovir dose is 900 mg (two 450 mg tablets) once a day, starting within 10 days of transplantation until 200 days post-transplantation.
How to Use Valgan Tablets by Cipla
General advice:
Always follow your doctor’s or healthcare providers dosage recommendation. Take the medication at the exact time that has been recommended with or without food. Taking medication before eating, after eating, or sometimes several hours before/ after eating has an impact on how the tablet is broken down in your body and absorbed. If a medication is to be taken twice daily am and pm then try to take the medication exactly 12 hours apart. This way you will have an even dosage in your body with higher efficiency and less side effects.
You should always take your medication on time. If you miss a dose then take it as soon as you remember unless it is almost time for the next dose. In that case, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Specific recommendation for Valgan (Valganciclovir 450 mg tablets):
Take Valgan tablets with food. Do not break or crush the tablets and avoid contact with your skin or eyes. Wash your skin well with soap and water or rinse your eyes well with plain water if you come in contact with the content of the tablet,
Do not run out of valganciclovir 450 mg tablets. The amount of virus in your blood may increase if your medicine is stopped, even for a short time.
If you take too much Valgan (Generic Valcyte), call your local poison control center or emergency room right away. You may need treatment in a hospital. Only adults should take Valgan.
Valgan (Generic Valcyte) Contraindications
Valgan tablets (Generic Valcyte) are contraindicated in patients with a hypersensitivity to Valganciclovir Hydrochloride, Ganciclovir or any inactive ingredient present in Valgan tablets.
Valganciclovir Side Effects
The most common Valganciclovir side effects and laboratory abnormalities reported by greater than or equal to 20% of adult patients are diarrhea, pyrexia, nausea, tremor, neutropenia, anemia, graft rejection, thrombocytopenia, and vomiting.
Our pharmacist’ general recommendation:
Immediately go to the nearest hospital or seek medical attention elsewhere if you experience a sudden allergic reaction or experience a hypersensitive reaction such as swollen limbs or face, difficulty in swallowing or breathing, hives, skin rash, of tight chest. Allergic reactions can intensify and become dangerous.
Specific side effects for Valgan by Cipla (Valganciclovir 450 mg) tablets:
Generic Valcyte can affect your blood cells and bone marrow causing serious and life-threatening problems. It can lower the amount of your white blood cells, red blood cells, and platelets. Your doctor may do regular blood tests to check your blood cells while you are taking Valgan. Based on these tests, your doctor may change your dose or tell you to stop taking Valgan.
Valgan may lower the amount of sperm in a man's body and cause fertility problems. Valganciclovir 450mg can affect your kidney, including serious problems such as kidney failure. Your doctor may do regular blood tests to check your kidney function while you are taking this medicine. Your doctor may adjust your dose based on these tests.
Common side effects of Valgan in adults and children include:
• diarrhea
• nausea, vomiting
• fever
• shaky movements (tremors)
• low white cell, red cell and platelet cell counts in blood tests
• rejection of the transplanted organ (graft)
Other common side effects in children include:
• constipation
• high blood pressure
• cough and colds
Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of this medicine. For more information, ask your doctor.
Warnings & Precautions When Using Generic Valcyte (Valgan Tablets)
The specific warnings and precautions to be taken when using Generic Valcyte are (Valganciclovir 450 mg tablets):
Do not take Valgan by Cipla if you are receiving hemodialysis. Do not take Valganciclovir 450 mg if you are allergic to valganciclovir (the active ingredient) or if you have ever had a serious allergic reaction to ganciclovir or Cytovene-IV. Symptoms of an allergic reaction to this medicine may include: sudden trouble breathing, wheezing, hives all over your body, swelling around your mouth, or feeling anxious.
Before taking Valgan by Cipla or any other brand of generic Valcyte, tell your doctors if you:
• have kidney problems
• have blood cell problems
• are having radiation treatment
• have any other medical conditions
This medicine may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether this medicine passes into breast milk or if it could harm a nursing baby. Do not use this medicine without telling your doctor if you are breast-feeding a baby.
Tell your doctor about all the medicines you take such as vitamins and herbal supplements. Valgan by Cipla and other medicines may affect each other and cause serious side effects. Especially tell your doctor if you take:
• didanosine (Videx)
• zidovudine (Retrovir, Trizivir, Combivir)
• probenecid (Col-Probenecid, Probenecid, and Colchicine)
• mycophenolate mofetil (CellCept)
Valgan can cause seizures, sleepiness, dizziness, unsteady movements, and confusion. You should not drive a car or operate other dangerous machinery until you know how this medicine affects you.
Some drugs interact with other drugs and may become ineffective or increase the effect of the medication. It is therefore important that you inform your doctor or pharmacist about all the medications you are currently taking or have been taking within the last 14 days before starting on a new medicine. You can also send us an email with the medications and our qualified pharmacist will check for potential drug interactions free of charge.
Women must always inform their doctor or pharmacist if they plan to become pregnant or if they are already pregnant as certain medication can be harmful to the unborn child. It is equally important to inform if you are breastfeeding because many medications are passed through the breast milk and may have a serious effect on your baby.
Lastly, your doctor or pharmacist needs to know if you have any known allergies or special medical conditions so they can prescribe a medication that is safe for you to take.
Valganciclovir During Pregnancy
Valganciclovir has been classified by the US FDA as Pregnancy Category C. After oral administration, valganciclovir (prodrug) is converted to Ganciclovir (active drug) and, therefore, Generic Valcyte is expected to have reproductive toxicity effects similar to Ganciclovir.
During animal studies, it was observed that Ganciclovir caused maternal and fetal toxicity and embryo-fetal mortality in pregnant mice and rabbits as well as teratogenicity in rabbits at exposures two-times the human exposure. There is no available human data at present regarding the use of Valganciclovir or Ganciclovir in pregnant women to establish the presence or absence of drug-associated risk.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.
Nursing Considerations
It is not known whether Valganciclovir or Ganciclovir are excreted in human milk. It has been observed that Valganciclovir caused granulocytopenia, anemia and thrombocytopenia in clinical trials and ganciclovir was mutagenic and carcinogenic in animal studies, serious adverse events can occur from Ganciclovir exposure in nursing infants.
Do not use this medication without telling your doctor if you are breast-feeding a baby.
Buy Generic Valcyte Pills Online at Only $18.73 per Pill
You can buy Generic Valcyte tablets online from Clear Sky Pharmacy at a cheap price. Valgan 450 mg pills, manufactured by Cipla Ltd., India are supplied in a box of 4 tablets. The 450 mg tablets cost only $18.73 per unit when you place an order for 52 tablets.
Disclaimer
The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.
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