Generic Pioglitazone Tablets

Generic Pioglitazone (Pioz Tablets) - Product Information

Generic Pioglitazone HCl 15mg (Pioz Tablets) is used along with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus either alone or in combination with a sulfonylurea, metformin, or insulin.
Pioglitazone tablets (Pioz 15 mg), must not be used to treat type 1 diabetes or diabetic ketoacidosis, since it exerts its antihyperglycemic effect only in the presence of endogenous insulin. Hence it would not be effective to treat patients with Type 1 diabetes mellitus.

Pioz tablets are manufactured by USV Private Limited, India in the strengths of 15 mg and are available online at a cheap price of only $0.27 per tablet. This the cheapest Generic Pioglitazone without insurance.   We also have in stock Generic Glucophage (Glycomet Tablets) which is also used along with diet and exercise in the treatment of type 2 diabetes mellitus.

Name of the Drug

We supply original Pioz tablets manufactured by USV Private Limited, India .

Manufacturer of Pioz Tablets

USV Private Limited 
Website: www.usvindia.com

Active Ingredient present in Pioz Tablets

The active ingredient present in Pioz tablets is Pioglitazone Hydrochloride. Each Pioz tablet contains Pioglitazone Hydrochloride equivalent to 15 mg of Pioglitazone.

What is Generic Pioglitazone (Pioz Tablets by USV) Used For?

The active ingredient present in Pioz 15 mg is called Pioglitazone Hydrochloride. It may be taken alone or with other diabetes medicines. This medicine is used in treatment of diabetes along with diet and exercises to improve blood sugar (glucose) control in adults with type 2 diabetes.
Type 2 diabetes is an medical condition where the body does not make enough insulin, or the insulin that it makes doesn't work properly. This can cause high blood sugar levels (hyperglycaemia). Pioglitazone tablets help to control your blood sugar levels by helping your body make better use of the insulin it produces.

Is There A Generic For Pioglitazone (Actos)?

On August 17 2012, the FDA approved generic versions of Actos (Pioglitazone Hydrochloride), a once-daily oral tablet for the treatment of type 2 diabetes originally sold by Takeda. Several companies sell generic versions of the drug. Pioz Tablets by USV Limited, India is also a generic version of this medication.

Pioz (Generic Pioglitazone Tablets) - Dose

Pioglitazone tablets (Pioz) should be taken once daily and can be taken with or without meals. The recommended starting dose of Pioz tablets for patients without congestive heart failure is 15 mg or 30 mg once daily.The recommended starting dosage for patients with congestive heart failure (NYHA Class I or II) is 15 mg once daily.

In case of inadequate glycemic control, the dose can be titrated in increments of 15 mg up to a maximum of 45 mg once daily based on glycemic response of the individual patient as determined by HbA1c. After initiation of Pioglitazone tablets or with dose increase, monitor patients carefully for side effects related to fluid retention such as weight gain, edema, and signs and symptoms of congestive heart failure.

Liver tests (serum alanine and aspartate aminotransferases, alkaline phosphatase, and total bilirubin) should be obtained before starting treatment with Pioglitazone tablets. In case of abnormal liver tests, use caution when treating with Generic Pioglitazone. Routine periodic monitoring of liver tests during treatment with Pioglitazone tablets are not recommended in patients without liver disease.

How to Use Generic Pioglitazone (Pioz Tablets by USV)

Take Generic Pioglitazone Hydrochloride (Pioz tablets) exactly as your doctor tells you to take it. Your doctor may change your dose of this medicine. Do not change the medicine dose unless your doctor tells you to. This medicine may be prescribed alone or with other diabetes medicines. This will depend on how well your blood sugar is controlled

Take this medicine 1 time each day, with or without food. If you miss a dose of this medicine, take your next dose as prescribed unless your doctor tells you differently. Do not take two doses at one time the next day. If you take too much this medicine, call your doctor or go to the nearest hospital emergency room right away.

If your body is under stress such as from a fever, infection, accident, or surgery the dose of your diabetes medicines may need to be changed. Call your doctor right away.

Stay on your diet and exercise programs and test your blood sugar regularly while taking this medicine. Your doctor should do certain blood tests before you start and while you take this medicine. Your doctor should also do hemoglobin A1C testing to check how well your blood sugar is controlled with this medicine. Your doctor should check your eyes regularly while you take this medicine.
It may take 2 to 3 months to see the full effect of this medicine on your blood sugar level.

Pioglitazone Side effects

The most common side effects of Pioglitazone tablets (Pioz) with an incidence rate of 5% or more include:
• cold-like symptoms (respiratory tract infection)
• headache
• sinus infection (sinusitis)
• muscle pain (myalgia)
• sore throat (pharyngitis)

Pioglitazone tablets may cause serious side effects including:
1. Liver problems, call your doctor right away if you have:
• nausea or vomiting
• stomach pain
• unusual or unexplained tiredness
• loss of appetite
• dark urine
• yellowing of your skin or the whites of your eyes

2. Broken bones (fractures). Usually in the hand, upper arm, or foot in women. Talk to your doctor for advice on how to keep your bones healthy.

3. Low blood sugar (hypoglycemia). This can happen if you skip meals, if you also use another medicine that lowers blood sugar, or if you have certain medical problems. Lightheadedness, dizziness, shakiness, or hunger may happen if your blood sugar is too low. Call your doctor if low blood sugar levels are a problem for you.

4. Diabetic eye disease with swelling in the back of the eye (macular edema). Tell your doctor right away if you have any changes in your vision. Your doctor should check your eyes regularly.

5. Release of an egg from an ovary in a woman (ovulation) leading to pregnancy. Ovulation may happen when premenopausal women who do not have regular monthly periods take this medicine. This can increase your chance of getting pregnant.

6. Bladder cancer. There may be a small chance of bladder cancer with this medicine. This is still being tested. Tell your doctor right away if you see blood or a red color in your urine.

7. Fluid retention. This medicine can cause your body to keep extra fluid, which leads to swelling (edema) and weight gain. Extra body fluid can make some heart problems worse or lead to heart failure. Heart failure means your heart does not pump blood well enough.

Do not take this medicine if you have severe heart failure. If you have heart failure with symptoms (such as shortness of breath or swelling), even if these symptoms are not severe, this medicine may not be right for you

Call your doctor right away if you have any of the following:
• swelling or fluid retention, especially in the ankles or legs
• shortness of breath or trouble breathing, especially when you lie down
• an unusually fast increase in weight
• unusual tiredness

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all the side effects of this medicine. For more information, ask your doctor or pharmacist.

Warnings & Precautions When Using Pioz Tablets (Generic Pioglitazone)

Do not take Pioz Tablets (Generic Pioglitazone) if you:
• have severe heart failure. Thiazolidinediones, including Pioz, cause or exacerbate congestive heart failure in some patients.
• are allergic to Pioglitazone Hydrochloride or any inactive ingredient in this medicine
• After initiation of Pioglitazone tablets, and after dose increases, monitor patients carefully for signs and symptoms of heart failure (e.g., excessive, rapid weight gain, dyspnea, and/or edema). If heart failure develops, it should be managed according to current standards of care and discontinuation or dose reduction of Pioglitazone must be considered.
• Pioz tablets are not recommended in patients with symptomatic heart failure.
• Congestive heart failure: Fluid retention may occur and can exacerbate or lead to congestive heart failure. Combination use with insulin and use in congestive heart failure NYHA Class I and II may increase risk. Monitor patients for signs and symptoms.
• Edema: Dose-related edema may occur.
• Hepatic effects: Postmarketing reports of hepatic failure, sometimes fatal. Causality cannot be excluded. If liver injury is detected, promptly interrupt Pioz and assess patient for probable cause, then treat cause if possible, to resolution or stabilization. Do not restart Pioz tablets if liver injury is confirmed and no alternate etiology can be found.
• Fractures: Increased incidence in female patients. Apply current standards of care for assessing and maintaining bone health.
• Bladder cancer: Preclinical and clinical trial data, and results from an observational study suggest an increased risk of bladder cancer in pioglitazone users. The observational data further suggest that the risk increases with duration of use. Do not use in patients with active bladder cancer. Use caution when using in patients with a prior history of bladder cancer.
• Hypoglycemia: When used with insulin or an insulin secretagogue, a lower dose of the insulin or insulin secretagogue may be needed to reduce the risk of hypoglycemia.
• Macular edema: Postmarketing reports. Recommend regular eye exams in all patients with diabetes according to current standards of care with prompt evaluation for acute visual changes.
• Macrovascular outcomes: There have been no clinical studies establishing conclusive evidence of macrovascular risk reduction with Pioz or any other anti-diabetic drug.

Talk to your doctor before taking Pioglitazone HCl tablets if you have either of these conditions.

Before you start taking this medicine, tell your doctor if you:
• have type 1 ("juvenile") diabetes or had diabetic ketoacidosis
• have a type of diabetic eye disease that causes swelling in the back of the eye (macular edema)
• have liver problems
• are a premenopausal woman (before the "change of life") who does not have periods regularly or at all.

This medicine may increase your chance of becoming pregnant. Talk to your doctor about birth control choices while taking this medicine.
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

Pioz Tablets (Generic Pioglitazone) and some of your other medicines can affect each other. You may need to have your dose of this medicine or certain other medicines changed.
It is not known if this medicine is safe and effective in children.

Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist before you start a new medicine. They will tell you if it is okay to take this medicine with other medicines.

Pioglitazone (Pioz Tablets) During Pregnancy

Pioglitazone Hydrochloride (Pioz tablets) has been classified by the US FDA as Pregnancy Category C. There are no adequate and well-controlled studies of Pioglitazone Hydrochloride conducted in pregnant women. Animal studies have demonstrated increased rates of post-implantation loss, delayed development, reduced fetal weights, and delayed parturition at doses 10 to 40 times the maximum recommended human dose.

Pioglitazone Hydrochloride tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Inform your doctor immediately if you become pregnant while taking this medicine. Talk to your doctor if you are pregnant or plan to become pregnant about the best way to control your blood glucose levels while pregnant.

Pioglitazone Tablets During Breastfeeding

It is not known whether Pioglitazone Hydrochloride is secreted in human milk or if it can harm your baby. Pioglitazone is secreted in the milk of lactating rats. Because many drugs are excreted in human milk, and because of the possibility for Pioglitazone Hydrochloride to cause serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue Pioglitazone Hydrochloride, taking into account the importance of Pioglitazone Hydrochloride to the mother.

You should not take Pioz tablets if you breastfeed your baby. Talk to your doctor about the best way to control your blood glucose levels while breastfeeding.

Buy Generic Pioglitazone 15 mg Tablets Online at Only $0.27 per Pill

You can buy Generic Pioglitazone Hydrochloride 15 mg tablets online from Clear Sky Pharmacy at a cheap price. Pioz 15 mg pills, manufactured by USV Private Limited, India are supplied in a blister strip of 10 tablets. The 15 mg tablets cost only $0.27 per unit when you place an order for 300 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

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