Generic Gabapentin

Generic Gabapentin (Gabasign Capsules and Tablets) - Product Information

Generic Gabapentin (Gabasign Capsules and Tablets) belongs to a group of medicines called anticonvulsants and is used to treat epilepsy, a condition in which the patient has repeated seizures (fits) ranging from mild to severe. This medicine is also used to treat neuropathic pain, a type of pain caused by damage to the nerves.

Gabasign capsules and tablets are manufactured by HAB Pharmaceuticals & Research Ltd. (Signature), India in the strengths of 300 mg (capsules), 600 mg (tablets) and 800 mg (tablets) and are priced at $0.38 a capsule for 300 mg strength. This is cheapest price for Gabapentin without insurance.
We also have in stock Generic Topamax (Topirol tablets) which is used for the treatment of epilepsy with partial onset or primary generalized tonic-clonic seizures.

Name of the Drug

We supply original Gabasign capsules and tablets manufactured by HAB Pharmaceuticals & Research Ltd. (Signature), India.

Who Makes Generic Gabapentin? - Manufacturer of Gabasign Capsules and Tablets

HAB Pharmaceuticals & Research Ltd. (Signature)  
Website: www.habpharma.in

How Much Does Generic Gabapentin Cost?

Generic Gabapentin 300 mg capsules cost only $0.38 a capsule, 600 mg strength cost only $0.50 a tablet, whereas the 800 mg version costs $0.65 a tablet.

Active Ingredient present in Gabasign Capsules and Tablets

The active ingredient present in Gabasign capsules and tablets is Gabapentin. Each capsule or tablet contains 300 mg, 600 mg or 800 mg of the active ingredient Gabapentin.

Uses of Generic Gabapentin (Gabasign)

Generic Gabapentin (Gabasign) is used with other medications to prevent and control seizures. It is used for adjunctive therapy in the treatment of partial onset seizures, with and without secondary generalization, in adults and pediatric patients 3 years and older with epilepsy. It is also used to relieve nerve pain (Postherpetic neuralgia) following shingles (a painful rash due to herpes zoster infection) in adults. Gabapentin is known as an anticonvulsant or antiepileptic drug.

Mechanism of Action

The mechanism by which Gabapentin (Gabasign) exerts its anticonvulsant action is unknown. In vitro studies with radio labelled Gabapentin have characterised a novel peptide binding site in rat brain tissues including neocortex and hippocampus that may relate to anticonvulsantactivity of Gabapentin and its structural derivatives.
Gabapentin at relevant clinical concentrations does not bind to other common medicine or neurotransmitter receptors of the brain. Gabapentin slightly reduces the release of monoamine neurotransmitters in vitro.
Gabapentin administration to rats increases GABA turnover in several brain regions in a manner similar to valproate sodium, although in different regions of brain.

Generic Gabapentin (Gabasign) - Dosage

The dosage of Generic Gabapentin (Gabasign) for various indications is given below:
Postherpetic Neuralgia:
The dose can be titrated up as needed to a dose of 1800 mg/day
Day 1: Single 300 mg dose
Day 2: 600 mg/day (i.e., 300 mg two times a day)
Day 3: 900 mg/day (i.e., 300 mg three times a day)

Epilepsy with Partial Onset Seizures:
Patients 12 years of age and older: starting dose is 300 mg three times daily; may be titrated up to 600 mg three times daily.
Patients 3 to 11 years of age: The starting dose range is 10 to 15 mg/kg/day, given in three divided doses; recommended dose in patients 3 to 4 years of age is 40 mg/kg/day, given in three divided doses.
Patients 5 to 11 years of age: The recommended dose in patients 5 to 11 years of age is 25 to 35 mg/kg/day, given in three divided doses.

The recommended dose is reached by upward titration over a period of approximately 3 days.Dose should be adjusted in patients with reduced renal function.

Generic Gabapentin (Gabasign) Storage

Store Generic Gabapentin (Gabasign capsules and tablets) at controlled room temperature (59°F to 86°F, 15°C to 30°C). Protect from light.

Gabasign Contraindications

Gabasign capsules and tablets are contraindicated in patients with a hypersensitivity to Gabapentin or any inactive ingredient present in tablets. Gabasign capsules and tablets are also contraindicated in the following cases:

Warnings and Precautions

• Drug Reaction with Eosinophilia and Systemic Symptoms (Multiorgan hypersensitivity): Discontinue if alternative etiology is not established
• Anaphylaxis and Angioedema: Discontinue and evaluate patient immediately
• Driving Impairment; Somnolence/Sedation and Dizziness: Patients should be warned not to drive until they have gained sufficient experience to assess whether their ability to drive or operate heavy machinery will be impaired
• Increased seizure frequency may occur in patients with seizure disorders if Generic Gabapentin (Gabasign) is abruptly discontinued. Patients should not stop using this medicine suddenly without asking their doctor. They may need to slowly decrease your dose before stopping it completely.
• Suicidal Behavior and Ideation: Monitor for suicidal thoughts/behavior
• Neuropsychiatric Adverse Reactions in Children 3 to 12 Years of Age: Monitor for such events
• Make sure the doctor knows that the patient is pregnant or breastfeeding, or if they have kidney disease.
• In case a test is done for protein in the urine, patients should tell the healthcare provider that they are using this medicine.

Driving and Using Machines

This medicine may make you dizzy or drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

Generic Gabapentin (Gabasign) Side Effects

Most common Generic Gabapentin side effects with an incidence rate of 8% or more and at least twice that for placebo were:
Postherpetic neuralgia: Dizziness, somnolence, and peripheral edema
Epilepsy in patients greater than 12 years of age: Somnolence, dizziness, ataxia, fatigue, and nystagmus
Epilepsy in patients 3 to 12 years of age: Viral infection, fever, nausea and/or vomiting, somnolence, and hostility.
Call your doctor immediately if you notice any of these side effects:

• Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling in the mouth or throat, tightness in chest, trouble breathing
• Clumsiness, problems with coordination
• Extreme tiredness, slurred speech
• Uncontrolled eye movement

Gabapentin (Gabasign Capsules and Tablets) Overdosage

A lethal dose of Gabapentin (Gabasign Capsules and Tablets) was not identified in mice and rats receiving single oral doses as high as 8000 mg/kg. Signs of acute toxicity in animals included ataxia, labored breathing, ptosis, sedation, hypoactivity, or excitation.
Acute oral overdoses of Gabapentin up to 49 grams have been reported. In these cases, double vision, slurred speech, drowsiness, lethargy, and diarrhea were observed. All patients recovered with supportive care. Coma, resolving with dialysis, has been reported in patients with chronic renal failure who were treated with Gabapentin capsules and tablets.
Gabapentin can be removed by hemodialysis. Although hemodialysis has not been performed in the few overdose cases reported, it may be indicated by the patient’s clinical state or in patients with significant renal impairment.

Gabapentin During Pregnancy

Gabapentin (Gabasign Tablets) has been classified by the US FDA as Pregnancy Category C. In nonclinical studies conducted in mice, rats, and rabbits, Gabapentin was developmentally toxic when administered to pregnant animals at doses similar to or lower than those used clinically.
There are no adequate and well-controlled studies conducted in pregnant women. Gabapentin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Stop using this medication and inform your doctor immediately in case you become pregnant during treatment. Therefore you must inform your physician if you are pregnant, or if you are planning to become pregnant, or if you become pregnant while you are taking Gabapentin capsules.

Gabapentin Nursing Considerations

It has been proved that Gabapentin is secreted into human milk following oral administration. A nursed infant could be exposed to a maximum dose of approximately 1 mg/kg/day of Gabapentin.
Since the effect on the nursing infant is unknown, Gabapentin capsules should be used in women who are nursing only if the benefits clearly outweigh the risks.
Do not use this medicine without telling your doctor if you are breast-feeding a baby. You should inform your doctor if you are breast-feeding an infant.

Buy Generic Online at Only $0.38 per Capsule

You can buy Generic online from Clear Sky Pharmacy at a cheap price. Gabasign 300 mg, 600 mg and 800 mg pills, manufactured by manufactured by HAB Pharmaceuticals & Research Ltd. (Signature),, India are supplied in a blister strip of 10 capsules. The cost of Gabapentin generic (Gabasign 300 mg capsules) is only $0.38 per unit when you place an order for 400 capsules. This is cheapest price for Gabapentin without insurance.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

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