Generic Combivir (duovir By Cipla)

Generic Combivir (Duovir Tablets) - Product Information

Generic Combivir (Duovir tablets) is a medicine containing Lamivudine and Zidovudine which is used for the treatment of HIV infection in adults and children weighing more than 30 kg. Duovir tablets is always used in combination with other HIV medicines.

Duovir tablets are manufactured by Cipla Ltd. in the strengths of 450 mg (Lamivudine 150 mg and Zidovudine 300 mg). We also have in stock Atazanavir Sulfate Capsules (Atavir by Cipla) which are also used to treat the same indications.

Name of the Drug

We supply original Duovir tablets manufactured by Cipla Ltd..

Manufacturer of Duovir Tablets

Cipla Ltd. 
Website: cipla.com

Active Ingredients present in Duovir Tablets

The active ingredients present in Duovir tablets are Lamivudine and Zidovudine. Each tablet of Duovir contains 150 mg of Lamivudine and 300 mg of Zidovudine

Uses of Generic Combivir (Duovir by Cipla)

This medicine is used to treat HIV. It helps to keep the HIV virus from reproducing in the body. The medicine is an antiviral medication containing a combination of lamivudine and zidovudine. These medicines are in a group of human immunodeficiency virus (HIV) medicines called reverse transcriptase inhibitors. This medication is not a cure for HIV or AIDS.

Lamivudine And Zidovudine Tablets (Duovir) - Dosage

The dosage of Lamivudine And Zidovudine Tablets (Duovir) is given below.

Dose for Adults and Adolescents weighing 30 kg or More:
1 tablet of Duovir twice daily.

Dose for Pediatrics:
Duovir dosage should be based on body weight not to exceed adult doses.

Generic Combivir, which is a fixed-dose combination medication, should not be administered to pediatric patients weighing less than 30 kg or patients requiring dosage adjustment, such as those with renal or hepatic impairment, or patients experencing dose-limiting adverse reactions.

How to Use Lamivudine And Zidovudine Tablets (Generic Combivir)

Take Lamivudine And Zidovudine tablets exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. It can be taken with or without food.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Do not change your doses of medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

Duovir can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly.

If you have hepatitis B you may develop liver symptoms after you stop taking this medicine, even months after stopping. Your doctor may want to check your liver function for several months after you stop using this medicine. Visit your doctor regularly.

Missed Dose Instructions

If you miss a dose of Generic Combivir ( Lamivudine And Zidovudine tablets), take the missed dose as soon as you remember it. In case it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses of the medicine at the same time to make up for a missed dose.

Generic Combivir (Duovir Tablets) Contraindications

Generic Combivir tablets (Duovir) are contraindicated in patients with a hypersensitivity e.g., anaphylaxis, Stevens-Johnson syndrome) to Lamivudine or Zidovudine or to any inactive ingredient present in Duovir tablets.

Duovir Side effects

The most commonly reported Duovir side effects with an incidence greater than or equal to 15% in adult and pediatric HIV-l during clinical studies of combination medicine Lamivudine and Zidovudine tablets were headache, nausea, malaise and fatigue, nasal signs and symptoms, diarrhea, and cough.

Get emergency medical help if you have any signs of an allergic reaction including: hives, difficult breathing, and swelling of your face, lips, tongue, or throat.

This medicine may cause lactic acidosis; a build-up of lactic acid in the body, which can be fatal. Lactic acidosis can start slowly and get worse over time.

Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:
• muscle pain or weakness
• numb or cold feeling in your arms and legs
• trouble breathing
• feeling dizzy, light-headed, tired, or very weak
• stomach pain, nausea with vomiting
• slow or uneven heart rate

Call your doctor at once if you have any of these other serious side effects of Generic Combivir:
• fever, chills, body aches, flu symptoms
• pale skin, easy bruising or bleeding, unusual weakness
• trouble swallowing, trouble standing up or climbing stairs
• liver problems, stomach pain, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes)
• pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate)
• white patches or sores inside your mouth or on your lips

Less serious Duovir side effects may include:
• changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and trunk)
• mild nausea, vomiting, diarrhea
• numbness or tingling
• sleep problems (insomnia)
• headache, dizziness, tired feeling
• cough, runny or stuffy nose

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Overdose symptoms may include nausea, vomiting, headache, dizziness, drowsiness, confusion, and seizure (convulsions).

Duovir Tablets (Generic Combivir) Storage Instructions

Store Duovir tablets (Generic Combivir) between 36°F and 86°F (2°C to 30°C). Throw away Duovir that is no longer needed or expired (out of date). Keep Generic Combivir and all other medicines out of reach of children and pets.

Warnings & Precautions When Using Duovir Tablets (Generic Combivir)

Do not use this medicine if you are allergic to lamivudine or zidovudine (the active ingredients). This medicine should not be taken together with any other medications that contain either of the two drugs. This includes Epivir®, Retrovir®, Epzicom® (abacavir and lamivudine), and Trizivir® (abacavir, lamivudine, and zidovudine).

To make sure you can safely take this medicine, tell your doctor if you have any of these other conditions:
• kidney disease
• liver disease (including hepatitis)
• pancreatitis
• bone marrow suppression
• problems with your muscles

Some people develop a life-threatening condition called lactic acidosis while taking this medicine. You may be more likely to develop lactic acidosis if you are overweight or have liver disease, if you are a woman, or if you have taken HIV or AIDS medications for a long time. Talk with your doctor about your individual risk.

This medicine may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection. Taking this medicine will not prevent you from passing HIV to other people. Avoid having unprotected sex or sharing razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex.

Lamivudine And Zidovudine Tablets (Generic Combivir) During Pregnancy

Lamivudine And Zidovudine Tablets (Generic Combivir) have been classified by the US FDA as Pregnancy Category C.
There are no adequate and well-controlled studies of Generic Combivir (Lamivudine and Zidovudine) in pregnant women. Clinical trial data demonstrate that maternal Zidovudine treatment during pregnancy reduces vertical transmission of HIV-1 infection to the fetus.

Animal reproduction studies performed with Lamivudine And Zidovudine showed increased embryotoxicity and fetal malformations (Zidovudine), and increased embryo1etha1ity (Lamivudine). Generic Combivir should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Do not use this medicine without your doctor's consent in case you are pregnant.

Duovir Tablets (Generic Combivir) - Nursing Considerations

HIV-infected mothers should not breast-feed their infants to avoid risking postnatal transmission of HIV infection. Although no studies of Generic Combivir excretion in breast milk have been performed, Lactation studies performed with Lamivudine and Zidovudine show that both medicines are excreted in human breast milk.

Due to the fact that the potential for HIV transmission exists as well as the potential for serious adverse reactions in nursing infants, mothers should be instructed not to breast-feed if they are taking Lamivudine and Zidovudine tablets .

Buy Generic Combivir Pills Online at Only $1.08 per Pill

You can buy Generic Combivir tablets online from Clear Sky Pharmacy at a cheap price. Duovir 450 mg pills, manufactured by Cipla Ltd., India are supplied in a bottle with 60 tablets. The 450 mg (Lamivudine 150 mg and Zidovudine 300 mg) tablets cost only $1.08 per unit when you place an order for 360 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

Shipping Restriction